| Tubac's 5 Cultures |
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| Hohokam: | (300 B.C.) | |
| Tohoho O'odham, (Pima): | (400 A.D.) | |
| Spanish: | Missionaries begin trading with the Pima as early as 1645, Eventually leading to the establishment of the Presidio of San Ignacio de Tubac in 1752 | |
| Mexican: | Mexico gained independence from Spain in 1821 bringing Tubac under the flag of Mexico. | |
| American: | In 1853, with the Gadsden Purchase, Tubac becomes part of the United States. | |
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